Most children with HSP make a full recovery.
HSP is due to blood vessels becoming inflamed. This inflammation is called vasculitis. The vasculitis affects the small blood vessels in the skin, causing a rash (red or purple spots called purpura). It can also affect blood vessels around the joints, in the intestines and in the kidneys.
The cause of HSP is unknown. It might be triggered by bacterial or viral infections, medicines, insect bites or exposure to chemicals or cold weather. It occurs most often in the spring, usually after an upper respiratory infection, like a cold.
HSP usually affects children from 2 to 10 years of age, but it can happen in anyone. You can't catch HSP.
This may start out looking like red spots, bumps or raised skin welts which can be itchy. This quickly changes to small bruises or reddish-purple spots that are often raised. It usually appears on the buttocks, on the legs and around the elbows. Blisters and/or ulcers may develop in the affected areas.
The rash looks the same as the rash children with meningococcal disease can get. So, if your child has a fever with this rash, call an ambulance.
Pain and swelling in the joints (such as the knees and ankles) which can come and go and can move around from joint to joint.
This can come and go and in some cases can be severe.
This is caused by the blood vessels in the bowel becoming inflamed and can indicate more serious problems (such as an abnormal folding of the bowel called intussusception [1]).
This is caused by the blood vessels in the kidney becoming inflamed (irritated and swollen). Serious kidney problems don't happen very often, but they can occur.
Many children with HSP also have swelling over the backs of their feet and hands, and the scrotum in boys.
There is no specific laboratory test for the disease. Your doctor will diagnose HSP after looking at your child's signs and symptoms. Your doctor may order blood tests to exclude other conditions. If HSP is suspected, your child will have urine tests to look for possible kidney involvement.
Fortunately, HSP usually gets better without any treatment. Pain relief (such as paracetamol) can help the joint pain. You must follow the dosage instructions on the bottle. It is dangerous to give more than the recommended dose.
Your doctor may recommend a drug called prednisolone. This can help people with severe stomach pains or very painful joints.
The illness lasts 4 to 6 weeks in most patients. The rash (purpura) changes from red to purple, becomes rust-coloured and then fades completely.
About 3 in 10 of those with HSP can get it again, usually within 4 months of the initial illness. Repeat episodes of the illness are usually milder and shorter and more common in patients with kidney involvement.
Your doctor will want to check urine samples and blood pressure several times after the HSP goes away to check for kidney problems.
Most people with HSP get better over time without treatment and have no long-term problems. About 5 in 100 of those with HSP develop long-term kidney disease (called glomerulonephritis). This may occur in the first week or so of the illness, but there may be a delay of weeks or months before it appears.
Your doctor will want to check urine samples and blood pressure several times after the HSP goes away to check for kidney problems. These checks should go on for at least 6 months and some doctors recommend a blood pressure and urine check every year for life.
Return to your doctor or the hospital if your child has one or more of the following or if you are worried for any other reason:
This content has been adapted from The Royal Children's Hospital (Melbourne) Kids Health Info for parents: Henoch-Schonlein purpura (HSP) [2] [Accessed 28/05/2018]
Images of HSP (Henoch-Schonlein purpura) on this page have been reproduced, with permission, from the website of the New Zealand Dermatological Society Incorporated. [3] Published online at dermnet.org.nz [4]. See: Creative Commons Attribution-NonCommercial-NoDerivs 3.0 (New Zealand) https://creativecommons.org/licenses/by-nc-nd/3.0/nz/legalcode [5]
This page last reviewed 10 December 2018.
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Links
[1] https://kidshealth.org.nz/intussusception?language=mi
[2] http://www.rch.org.au/kidsinfo/fact_sheets/HenochSchonlein_Purpura_HSP/
[3] http://dermnet.org.nz
[4] https://dermnetnz.org/
[5] https://creativecommons.org/licenses/by-nc-nd/3.0/nz/legalcode
[6] https://kidshealth.org.nz/node/1891
[7] https://kidshealth.org.nz/contact?from=http%3A%2F%2Fkidshealth.org.nz%2Fprint%2F267